Friday, 28 August 2015

Nervous System - Medical Terminology

Absence seizure—form of seizure consisting of momentary clouding of consciousness and awareness of the person’s surroundings. These include petit mal seizures in children
Acetylcholine—neurotransmitter chemical released at the end of nerve cells
Akinetic—pertaining to, characterized by, or causing akinesia
Alzheimer disease—brain disorder marked by gradual and progressive mental deterioration (dementia), personality changes, and impairment of daily function. Characteristics are speech disturbance, restlessness, anxiety, depression. Genetic factors may be a cause. A mutation on chromosomes 14 has been linked familial cases
Amyloid—a protein. Deposit of amyloid occur in neruofibrillary tangles, senile plaque and blood vessels in Alzheimer’s disease
Amyotrophic lateral sclerosis—Lou Gehrig disease. Degenerative disorder of motor neurons in the spinal cord and brainstem. Signs are weakness and atrophy muscles in hands, forearms and legs; difficulty in swallowing and talking, dyspnea develop and respiratory muscles become affected
Analgesia-- absence of sensibility to pain
Anencephaly—a congenital brain malformation
Anesthesia—lack of normal sensation such as absence of touch or pain. Two common types of anesthesia are spinal and epidural block
Anesthetics—agents that reduce or eliminate sensation. General and local
Aneurysm—enlarged, weakened area in an arterial wall, which may rupture, leading to hemorrhages and CVA (stroke)
Aphasia—difficult with speech
Apraxia—movements and behavior are not purposeful.
Arachnoid membrane—the second layer of the meninges surrounding the brain and spinal cord. This spider like membrane is loosely attached to the other meninges by web like fiber, so there is a space for fluid between the fibers and the third membrane
Astrocytes cells—star like in appearance and transport water and salts between capillaries and neurons
Astrocytoma—malignant tumor of astrocytes (glial brain cells)
Ataxia—condition of decreased coordination. Persistent unsteadiness on the feet can be caused by a disorder involving the cerebellum. Lack of muscular coordination
Aura—peculiar sensation experienced by the affected person before onset of a seizure. Dizziness, numbness and visual or olfactory disturbance are examples of aura. Peculiar sensations that precede the onset of illness occurring before the onset of an attack of migraine or epileptic seizure
Autonomic nervous system—The peripheral nervous system also functions involuntarily and automatically, without conscious control. This system of nerve fibers carries impulses away from the central nervous system to the glands, heart, blood vessels and involuntary muscles found in the walls of tubes like the intestines and hollow organs such as stomach and urinary bladder. Some autonomic nerves are sympathetic nerves and others are parasympathetic nerves.
Axon—extending from the cell body, long process of a nerve fiber that generally conducts impulses away/ along from the body of the nerve cell.
Basal ganglia—group of cells that regulate intentional movements of the body
Bell palsy—paralysis on one side of the face. The likely cause is a viral infection
Blood brain barrier—They associates with blood vessels and regulate the passage of potentially harmful substances from the blood into the nerve cells of the brain, consists of special lining (endothelial) cells, which along with actrocytes separates capillaries from nerve cells. Blood brain barrier blocks drug access to brain tissue in chemotherapeutic drugs to treat brain tumors
Bradykinesia—abnormal slowness of movement
Brain tumor—neoplastic disorder, abnormal growth of brain tissue and meninges, most primary tumors arise from glial cell (gliomas) or the meninges. Types of gliomas include astrocytoma, oligodendroglioma and ependymoma. Tumor can cause swelling and hydrocephalus
Brain—controls body activities.
Brainstem—the pons and medulla are part of the brainstem. Posterior portion of brain that connects the cerebrum with the spinal cord
Cardiac center—slows the heart rate when the heart is beating too rapidly
Cauda equine—below the end of spinal cord, a fan of nerve fibers or collection of spinal nerves. Bundle of spinal nerves below the end of the spinal cord.
Causalgia—intense burning pain following injury to a sensory nerve
Cell body—contains the cell nucleus, the part of a neuron containing the nucleus but not incorporating the axon and dendrites. Also called soma
Central nervous system—consists of brain and spinal cord
Cephalgia—headaches may result from vasodilation of blood vessels in tissue surrounding the brain or from tension in neck and scalp muscles
Cerebellar—Involving the part of the brain (cerebellum), which controls walking, balance, and coordination
Cerebellopontine—Referring to the cerebellum and pons
Cerebellum, pons and medulla oblongata—structure within the brain lie in the back and below the cerebrum and connect the cerebrum with the spinal cord
Cerebellum—functions to coordinate voluntary movements and to maintain balance and posture
Cerebra contusion— type of traumatic disorder, bruising of brain tissue as a result of direct trauma to the head. It is usually associated with a fracture of the skull, as well as with edema and an increase in intracranial pressure.
Cerebral angiography—x ray imaging of the arterial blood vessels in the brain after injection contrast material. Diagnose vascular disease such as aneurysm, occlusion in the brain
Cerebral concussion—type of traumatic brain injury caused by a blow to the head.
Cerebral cortex— A thin mantle of gray matter about the size of a formal dinner napkin covering the surface of each cerebral hemisphere. The cerebral cortex is crumpled and folded, forming numerous convolutions (gyri) and crevices (sulci)
Cerebral edema—swelling
Cerebral hemispheres—the brain is divided in half, a right side and left side, each hemisphere is subdivided into four major lobes named for the cranial bones that overlie them. These lobes are frontal, parietal, Occipital and temporal, as well as gryi and sulci
Cerebral palsy—partial paralysis and or lack of muscular coordination caused by loss of oxygen or blood flow to the cerebrum during pregnancy
Cerebrospinal fluid (CSF)—circulates throughout the brain and spinal cord
Cerebrospinal fluid analysis—samples of CSF are examined. It measure protein, glucose, and red and white blood cells. CSF can also detect tumor cell, bacteria and viruses. These studies are used to diagnose infection, tumors or multiple sclerosis
Cerebrovascular accident—vascular disorder, disruption in the normal blood supply to the brain; stroke. This condition is also known as cerebral infarction, is the result of impaired oxygen supply to the brain. There are three types of stroke; thrombotic, embolic and hemorrhagic. The major risk of stroke is hypertension, diabetes, smoking and heart disease
Cerebrum—largest part of the brain, “thinking area”. on the surface of cerebrum, nerve cells lie in sheath which make up cerebral cortex. Thought, judgment, memory, association and discrimination are functions of cerebrum
Chorea—dance-like
Comatose—a coma is state of unconsciousness from which the patient cannot be aroused.
Complex partial seizure—common type, these patients have seizures that caused them to pause in whatever they are doing and have memory problems
Computed tomography of the brain—computerized x ray technique that generates multiple images of the brain and spinal. It is useful for fracture, visualizing blood and bone, bleeding and brain injury
Corpus callosum—lies in the center of the brain and connects the two hemispheres
Cranial nerves—12 pairs of nerves that carry impulses between the brain and the head and neck. The one exception is the 10th cranial nerve, called vagus nerve. Cranial nerves carry motor impulses from the cerebrum to muscles and glands and these produce movement and activity
Dementia—mental decline and deterorization

Demyelination—loss of myelin insulating the nerve fiber and characteristic of multiple sclerosis, an acquired illness affecting the central nervous system. Destruction of myelin on axons of neurons
Demyelination—loss of myelin insulation, prevents the conduction of nerve impulses through the axon and causes paresthesias, muscle weakness, unsteady gait and paralysis
Dendrites—are the branched fiber/projection of a neuron that is the first part to receive the nervous impulse and act to propagate the electrochemical stimulation received from other neural cells to the cell body, or soma, of the neuron from which the dendrites project. Electrical stimulation is transmitted onto dendrites by upstream neurons (usually their axons) via synapses which are located at various points throughout the dendritic tree. Dendrites play a critical role in integrating these synaptic inputs and in determining the extent to which action potentials are produced by the neuron.
Dopamine—CNS neurotransmitter made by cells in the basal ganglia. Deficiency in patient with Parkinson disease
Doppler ultrasound studies—sound waves detect blood flow in the carotid and intracranial arteries.
Dura mater—outermost and toughest membrane of the meninges, this thick, rough membrane contains channels (Dural sinuses) that contain blood. Subdural space, is below the Dural membrane
Dyskinesia—condition marked by involuntary, spasmodic movements.
Dyslexia—developmental reading disorder occurring when the brain does not properly recognize, process, and interpret language
Electroencephlography—recording of the electrical of the brain
Embolic—an embolus travels to the cerebral arteries and occludes a small vessel. It occurs very suddenly.
Embolus—clot of material that travels through the bloodstream and suddenly block the vessel
Encephalitis—Encephalitis is an inflammation of the brain, usually caused by a direct viral infection or a hyper-sensitivity reaction to a virus or foreign protein. Brain inflammation caused by a bacterial infection is sometimes called cerebritis.
Encephalopathy—any degenerative disease of the brain.
Ependymal cells—(Greek ependyma) line membranes within the brain and spinal cord where CSF is produced and circulates (helps from CSF)
Epidural hematomas—An accumulation of blood between the skull and the Dura mater
Epilepsies—Greek word meaning a laying hold of
Epilepsy—chronic brain disorder characterized by recurrent seizure activity. A Sudden discharge of electrical activity within the brain. Seizures are often symptoms of underlying brain pathologic conditions such as tumor, meningitis, vascular disease or a scar tissue from a head injury
Femoral nerve—lumbar nerve leading to and from the thigh (femur)
Gait—manner of walking
Gangilia—singular (gangilion) small collection of nerve cell bodies outside the brain and spinal cord
Glial (neuroglial) cells—make up its supportive, protective and connective tissues framework of central nervous system and help it ward off infection. It does not transmit impulses, far numerous than neurons and can reproduce. Types of glial—astrocytes cells, microglial cell, oligodendroglial cells and ependymal cells
Glioblastoma multiforme—most malignant form of astrocytoma
Glioblastoma—highly malignant tumor, gliomas are tumors of glial cells
Gyrus—plural gyri. Sheet of nerve cells that produces a rounded ridge on the surface of the cerebral cortex; convolution
Hemiparesis—affects either left or right side of the body.
Hemiplegia—results from brain injury or stroke, affecting left or right side of the body
Hemorrhages—a blood vessel, such as the cerebral artery, breaks and bleeding atherosclerosis, or high blood pressure
Herniated disk—common cause leading to pain, weakness or numbness down the leg
Herpes zoster (shingles)—infectious disorders, viral infection affecting peripheral nerves. Blister and pain spread along peripheral nerves caused by herpes virus, the same virus that cause chickenpox.
Human immunodeficiency virus (HIV) encephalopathy—infectious disorders, brain disease and dementia occurring with AIDS
Huntington disease (Huntington chorea)—hereditary disorder marked by degenerative changes in the cerebrum leading to abrupt involuntary movements and mental deterioration. It results in personality changes, along with choreic movements or the arms, legs and facial grimpacing; this disease is located on chromosome 4
Hydrocephalus—a congenital disorder in which abnormal accumulation of fluid in the brain. It can occurs in adults as a result of tumors and infection.
Hypalgesia—diminished sensation to pain
Hyperalgesia—increased sensitivity to pain
Hyperesthesia—a light touch with a pin ma provoke increased sensation.
Hyperkinesias—Pathologically increased muscular movement. Hyperactivity, especially in children. Amphetamines (CNS stimulants) are used to treat in children
Hypesthesia—diminished sensitivity to pain
Hypothalamus—blow the thalamus is also an important part of the brain. Contains neurons that control body temperature, sleep, appetite, sexual desire and emotion of fear and pleasure. It regulates the release of hormones from the pituitary glands at the base of the brain and integrates the activities of the sympathetic and parasympathetic nervous system
Ictal event—Latin—ictus, meaning blow or a stroke. Pertaining to a sudden, onset as with the convulsion of an epileptic seizure
Intrathecal injection—chemicals, such as chemotherapeutic drugs, can be delivered into the subarachnoid space
Irreversible coma (brain death)—complete unresponsitivity to stimuli and a flat electroencephalogram tracing
Leptomeningeal—the pia and arachnoid membranes are known as the leptomeninges because of thin and delicate structure. Pertaining to leptomeninges
Lumbar puncture—CSF is withdrawn from between two lumbar vertebrae for analysis. Informal name “spinal tap”
Lumbar puncture—spinal fluid can be withdrawn for diagnosis or relief of pressure on brain. A hollow needle is inserted into the lumbar region of the spinal column blow the region where the nervous tissue of the spinal cord ends
Lymphatic plexus—an interconnecting network of lymph vessels
Magnetic resonance angiography—produces images of blood vessels
Magnetic resonance imaging—magnetic field and pulses of radio wave energy create images of the brain and spinal cord. It useful to diagnose stroke and detect bleeding problem and head injury
Medulla oblongata—connects the spinal cord with the brain. Nerve tracts cross from right to left and left to right in the medulla oblongata. It contains three vital centers that regulate internal activities of the body; respiratory center, cardiac center and vasomotor center. A Part of the brain just below the spinal cord. Controls breathing, heartbeat and the size of blood vessels
Meningeal—pertaining to the meninges, the three layers of membranes covering the brain and spinal cord.
Meninges—three layers of connective tissue membranes that surrounds the brain and spinal cord
Meningioma—slowly growing benign tumor
Meningitis—infectious disorders, inflammation of the meninges; leptomeningitis—caused by bacteria (pyogenic meningitis) or virus (aseptic or viral meningitis). Fever and meningeal irritation, such as headache and a stiff neck
Meningocele—the meninges protrude to the outside of the body
Microglial cell—small cells with many branching processes, as phagocytes they protect neurons in response to inflammation. Remove waste products from the CNS
Migraine—severe, recurring, unilateral, vascular headache. Symptoms are known as aura. Sensitivity to sound and light and temporary visual and sensory disturbance.
Motor (efferent) nerves)—travel from the spinal cord and brain to muscles of the body, telling them
how to respond. It carries away messages from the brain and spinal cord to muscles and organs
Motor aphasia—is present when the patient knows what he or she wants to say but cannot pronounce it.
Motor apraxia—the inability to carry out planned movements or to handle small objects, although cognizant of the proper use of the object.
Multiple sclerosis—destruction of the myelin sheath on neurons in the CNS and its replacement by plaques of sclerotic tissue. It is a chronic disease often marked by long periods of stability and worsening. Can be seen on MRI. Probably involves an autoimmune disease of lymphocytes reacting against myelin
Myasthenia gravis—autoimmune neuromuscular disorder characterized by weakness of voluntary muscles. Antibodies block the ability of acetylcholine to transmit the nervous impulse from nerve to muscle cell. Onset of symptom usually is gradual, double vision (diplopia) and facial weakness
Myelin sheath—covering of white fatty tissue that surrounds and insulate the axon and speed transmission of the electrical impulse. It gives white appearance to the nerve fiber.
Myelin—a fatty tissue that can cover the axons
Myelomenngocele—spinal cord and meninges protrude
Myelopathy—the viral disease affects the gray matter of the spinal cord. Leading to paralysis of muscles that rely on the damaged neurons.
Myemeningocele—neural tube defect caused by failure of the neural tube to close during embryonic development. This occurs in infants born with spina bifida
Myoneural—pertaining to nerve terminations in muscles
Narcolepsy—sudden, uncontrollable compulsion to sleep. Amphetamines and stimulants drugs are prescribed to prevent attacks.
Nerve—macroscopic, cord like collection of fibers that carry electrical impulses, able to be seen with a naked eye. Consists of a bundle of dendrites and axons that travel together like strands of rope.
Nervous system—most complex system of human body and classified into two divisions. Central nervous system and peripheral nervous system
Neuralgia—trigeminal neuralgia involves flashes of pain radiating along the course of the trigeminal nerve
Neurasthenia—nervous exhaustion and fatique, often following depression or lack of nerve strength
Neurofibrillary tangles—bundles of fibrils in the cytoplasm of a neuron in the cerebral cortex
Neuron—an individual nerve cell, a microscopic structure, impulses pass along the parts of a nerve cell in a definite manner and direction. Functional cell of the nervous system
Neuropathy—a functional disturbance or pathological change in the peripheral nervous system, sometimes limited to noninflammatory lesions as opposed to those of neuritis
Neurotransmitter—chemical substance/messenger by neuron on which the transfer of the impulse across the synapse depends. It stimulates another cell, which can be a nerve cell, muscle cell or gland cell. Examples are acetycholine, norepinephrine, epinephrine (adrenaline), dopamine, serotonin and endorphine
Occlusion--blockage
Oligodendroglial cells—have few dendrites; these form the myelin sheath in the central nervous system. Also called oligodendrocyte
Palliative—relieving symptoms but not curing them
Palsy—paralysis complete or partial loss of motor function
Paraplegia—originally, a stroke on one side. The term means paralysis both legs and lower part of the body caused by injury or disease of the spinal cord or cauda equine
Parasympathetic nerves—normally acts as a balance for the sympathetic nerves. It also slows down heart rate, lower blood pressure and stimulates intestinal contractions to clear rectum.
Parenchyma—essential distinguishing tissue of an organ or system. Neurons and nerves are the parenchyma of the nervous system. In the brain and spinal cord, neurons, which conduct electrical impulse, are the parenchyma tissue.
Paresis—partial paralysis or weakness in muscles
Paresthesia—tingling, burning, and “pins and needles” sensations
Parkinson disease (parkinsonism)—degeneration of neurons in the basal ganglia, occurring in later life and leading to tremors, weakness of muscles, and slowness of movement. It is caused by a deficiency of dopamine. Typical “pill-rolling” tremor of hands and characteristics mask-like lack of facial expression
Peripheral nervous system—cranial nerves and spinal nerves, plexuses, peripheral nerves throughout the body. The cranial and spinal nerves who functions voluntary, helps the body respond to the changes outside world, they include sense receptors for eye sight, hearing and balance, smell and touch and sensory nerves. Nerves outside the brain and spinal cord
Pia mater—containing CSF, closest to the brain and spinal cord. It contains delicate/thin connective tissue with a rich supply of blood vessels
Pia-arachnoid—most physician refer to the pia and arachnoid together
Plexus—large network intersecting blood vessels and lymphatic vessels of nerves in the peripheral nervous system. The cervical, branchial and lumbaosacral plexuses are the examples that include cervical, lumbar and sacral nerves. 
Polio—gray matter

Polyneuritis—inflammation of several peripheral nerves simultaneously.
Pons—part of brainstem that literally means bridge. Contains nerve fiber tracts that connect the cerebellum and cerebrum with the rest of the brain.  Connection of Nerves to eyes and face
Positron emission tomography scan—radioactive glucose is injected and then detected in the brain to image the metabolic activity of the cell
Postictal events—neurologic symptoms such as weakness in epileptic patients after seizures
Quadriplegia—all four extremities limbs are paralyzed or are affected. Injury is at the cervical level of the spinal cord.
Radiculitis—inflammation of the spinal nerve roots
Radiculopathy—sciatica is a radiculopathy affecting the sciatic nerve root in the back.
Receptor—organ that receives a nervous stimulus and passes it on to afferent nerves. The skin, ear, eyes and taste buds are receptors
Rectal plexus—plexus of veins in the rectal region
Respiratory center---controls muscles of respiration in response to chemical
Sciatic nerve—beginning in a region of the hip. Nerve extending from the base of the spine down the thigh, lower leg and foot.
Sciatica—pain or inflammation along the course of the nerve
Semicomatose—refers to a stupor (unresponsiveness) from which a patient can be aroused
Senile plaques—Abnormal structures, composed of parts of nerve cells surrounding protein deposits, found in the brains of people with Alzheimer's disease
Sensory (afferent) nerves—carry messages related to changes in the environment toward the spinal cord and brain through receptor
Sensory aphasia—difficulty understanding language and many pronounce words easily but use them inappropriate
Spina bifida cystica—is more severe form with cyst-like protrusions
Spina bifida occulta—the vertebral defect is covered with the skin and evident only on x ray or other imaging examination. A neural tube defect
Spina bifida—congenital defects in the lumbar spinal column caused by imperfect union of vertebral parts.
Spinal cord—column of nervous tissue extending from the medulla oblongata to the second lumbar vertebra with the vertebral column. It carries all the nerves to ad from the limbs and lower part of the body and a pathway for impulses going to and from the brain. A cross section view of the spinal cord reveals an inner region of gray matter and an outer region of white matter
Spinal nerves—thirty one pairs of nerves arising from the spinal cord carry messages between the spinal cord and the chest, abdomen and extremities
Stereotactic radiosurgery—use of specialized instrument to locate and treat targets in the brain. A gamma knife (high-energy radiation beam) is used to treat deep and inaccessible intracranial tumors and abnormal blood vessel masses without surgical incisions proton stereotactic radiosurgery delivers and uniform dose of proton radiation to a target and spares surrounding normal tissue
Stimulus— A factor capable of eliciting a response in a nerve,begin as impulse in the branching fibers of the neuron, which are called dendrites. An agent of change in the internal and external environment that evoke response
Stroma—of an organ is the connective and supportive tissue of an organ. Stromal tissue of the nervous system consists of the glial (neuroglial) cells.
Subarachnoid space—the space between the arachnoid membranes and the pia mater membranes. It contains cerebrospinal fluid.
Subdural hematomas—A subdural hematoma is a collection of blood in the space between the outer layer (dura) and middle layers of the covering of the brain (the meninges)
Sulcus—plural sulci. Depression or groove in the surface of the centebral cortex. Fissure
Sympathetic nerves—stimulate the body in times of stress and crises, they increase heart rate and forcefulness, dilate airways for more oxygen can increase blood pressure, it stimulate the adrenal glands to secrete epinephrine(adrenaline), while also inhibiting intestinal contractions for slow digestion
Synapse—the space where they nervous impulse jumps from one neuron to another. A space through which nervous impulses travels between the nerve cells or between the nerve and muscle or glandular cells
Syncopal—sudden and temporary loss of consciousness caused by inadequate flow of blood to the brain
Syncope—fainting
Tardive dyskinesia—irreversible neurological disorder of involuntary movements may develop in people who receive certain antipsychotic drugs for extended periods.
Temporal lobe epilepsy—seizure begins in the temporal lobe of the brain.
Terminal end fiber—the nervous impulses pass through the axon to leave the cell via the terminal end fibers of the neuron.
Thalamic—pertaining to the thalamus
Thalamus—important part of the brain, acts like a “triage center” and decides what is important and what is not, processing and relaying sensory information to the cerebral cortex. It also plays a major role in maintaining levels of awareness and consciousness. It conducts impulses between the spinal cord an cerebrum
Thrombotic—blood clot in the arteries leading to the brain, resulting in occlusion of the vessels. Atherosclerosis leads to this common type of stroke as blood vessels become blocked over time. Before total occlusion, a patient may experience symptoms that point to the gradual occlusion of blood vessels known as transient ischemic attacks
Thymectomy—method of treatment for myasthenia gravis. Removal of thymus gland
TIA—transient ischemic attack
Tics—an involuntary, compulsive, rapid, repetitive, stereotyped movement or vocalization, experienced as irresistible although it can be suppressed for some length of time (tourette syndrome)
Tonic-clonic seizures (grand mal or ictal events)—characterized by a sudden loss of consciousness, falling down and tonic contractions following by clonic contractions. These convulsion are often preceded by aura.
Tourette syndrome—involuntary, spasmodic, twitching movements; uncontrollable vocal sounds and inappropriate words.
Trigeminal nerve—5th cranial nerve

Vagal—this cranial nerve has branches to the head and neck, as well as to the chest
Vagus nerve—10th cranial nerve, branches reach to larynx, trachea, bronchi, lungs, aorta, esophagus and stomach. Carries messages to and from the neck, chest and abdomen.
Vasomotor center—affects the muscle in the walls of blood vessels, thus influencing blood pressure
Ventricles—spaces or canals in the middle of the cerebrum. They contain watery fluid through the brain and around the spinal cord. These fluids are cerebrospinal fluid and it protects the brain and spinal cord from shock by acting like a cushion. It usually clear and colorless and contains lymphocytes, sugar and proteins. Also found in heart, they are the two lower chambers of the heart
Vertebral plexus—plexus of veins related to the backbone

White and gray matters—the white nervous tissue, constituting the conducting portion of the brain and spinal cord, composed mostly of myelinated nerve fibers. Gray matter or substance is the term used to describe the tissues composed of unmyelinated fibers 

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